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大会报告

付向东
教授
美国加州大学圣地亚哥分校
报告题目：Cure Parkinson’s Disease by Converting Astrocytes into Neurons Directly in the Brain

个人简介
1982年毕业于武汉大学病毒学学系。1988年获凯西保留地（凯斯西储）大学生物化学博士学位，1992年获哈佛大学分子生物学博士后。现任美国加州大学圣地亚哥分校细胞与分子医学系教授、美国先进科学协会会员，RNA协会会员、白血病与淋巴癌协会委员、美国生物医学科学RayWu协会会员。

学习经历
1977-1982: 武大病毒系，本科
1983-1988: Case Western Reserve University, Biochemistry, 博士
1988-1992: Harvard University, 博后

主要工作经历与任职情况
1992-1998: Assistant Professor, UCSD
1998-2002: Associate Professor with Tenure, UCSD
2002-present: Full Professor, UCSD
2004-present: Lecture Professor, 武汉大学生科院
2011-present: 千人计划（B）

主要社会兼职
科技部蛋白质重大研究计划专家组成员

代表论文

Xue, Y-C., Zhou, Y., Wu, T-B., Zhu, T., Ji, X., Zhang, C., Kwon, Y-S., Yeo, G., Sun, H., Fu, X-D.*, and Zhang, Yi* (2009). Genome-wide analysis of PTB-RNA interactions reveals a strategy used by the general splicing repressor to modulate exon inclusion or skipping. Molecular Cell, 36:996-1006. (*co-corresponding authors).
Ji, X and Fu, X-D. (2012). The mediator couples transcription and splicing. Molecular Cell, 45:433-434.
Xiao, R., Tang, P., Yang, B., Huang, J., Zhou Y., Shao C-W., Li, H., Sun, H., Zhang, Y., and Fu, X-D. (2012). Nuclear matrix factor hnRNP U/SAF-A exerts a global control of alternative splicing by regulating U2 snRNP maturation. Molecular Cell, 45:656-668.
Xue, Y-C., Ouyang, K., Huang, J., Zhou, Y., Ouyang, H., Li, H., Wang, G., Wu, Q., Wei, C., Bi, Y., Jiang, L., Cai, Z., Sun, H., Zhang, K., Zhang, Y., Chen, J., and Fu, X-D. (2013) Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell, 152:82-96.
Ji, X., Zhou, Y., Pandit, S., Huang, J., Li, H., Lin, C. L., Rui, X., Burge, C. B., and Fu, X-D. (2013). SR proteins collaborate with 7SK and promoter-associated nascent RNA to release paused polymerase. Cell, 153:855-868.